Research, all articles

Ramon Velazquez, Eric Ferreira, Wendy Winslow, Nikhil Dave, Ignazio S. Piras, Marcus Naymik, Matthew J. Huentelman, An Tran, Antonella Caccamo & Salvatore Oddo Abstract The lack of effective treatments for Alzheimer’s disease (AD) is alarming, considering the number of people currently...

Abstract Excess adiposity or obesity has been inversely related to cognitive function and macular xanthophyll status. However, whether the neuroprotective effects of macular xanthophylls on cognitive function are independent of excess adiposity is unclear. We investigated the relationship...

Abstract Background Choline is an essential nutrient that is pivotal to proper brain development. Research in animal models suggests that perinatal choline deficiency influences neuron development in the hippocampus and cortex, yet these observations require invasive techniques. Objective...

ABSTRACT Rodent studies demonstrate that supplementing the maternal diet with choline during pregnancy produces life-long cognitive benefits for the offspring. In contrast, the two experimental studies examining cognitive effects of maternal choline supplementation in humans produced...

Abstract The American Medical Association (AMA) recently announced its recommendation to include choline in prenatal vitamins.1 Choline is an essential nutrient that is particularly important during pregnancy, as it impacts fetal brain development and can help prevent birth defects.2...

Abstract Background Severe iodine deficiency in pregnancy has major effects on child neurodevelopment, but less is known about the potential consequences of mild-to-moderate deficiency and iodine supplement use. Objective We explored the associations between maternal iodine intake and...

Choline is a dietary component essential for normal function of all cells. It, or its metabolites, assures the structural integrity and signaling functions of cell membranes; it is the major source of methyl-groups in the diet (one of choline's metabolites, betaine, participates in the...

Choline is a dietary component essential for normal function of all cells. In 1998 the National Academy of Sciences, USA, issued a report identifying choline as a required nutrient for humans and recommended daily intake amounts. In ongoing studies we are finding that men have a higher...